A very useful post detailing two methods on how to clone a VirtualBox VDI disk image.
You can find it here: http://www.modhul.com/2009/06/17/how-to-clone-or-copy-a-virtualbox-virtual-disk/
If you use VmWare with Debian-based Linux guests (Debian, Ubuntu, etc.) you probably have been annoyed by the following behaviour: You copy / move your guest, or in my case, you boot your guest both from Windows and from Linux; next time you try to boot, you have no network.
I've been running some OpenBSD guests on a Linux VmWare Server host with great success. Performance is great since OpenBSD is a light system packed with all the features you might need and VmWare Server does a great job virtualizing even this unsupported platform.