If you use VmWare with Debian-based Linux guests (Debian, Ubuntu, etc.) you probably have been annoyed by the following behaviour: You copy / move your guest, or in my case, you boot your guest both from Windows and from Linux; next time you try to boot, you have no network.
6to4 is one of the many transition mechanisms proposed by the IETF to ease the move towards an IPv6 internet. It is a tunneling protocol which encapsulates IPv6 packets in the payload of an IPv4 packet, with the added feature that the remote endpoint (the 6to4 Relay) of the tunnel configures itself automatically and uses a well-known anycast IPv4 address.